The amount of Arpimune ME 25mg Capsule you take depends on your weight, medical condition, and what you are taking it for. Your doctor will plan the correct dose for you. Do not change the dose without talking to your doctor. It can be taken with or without food. It is better to take it, in the same way, each time and at the same time every day to get the maximum benefit. Keep taking these tablets for as long as you have been told to, even if you feel well. Stopping treatment may increase the risk of your transplanted organ being rejected.